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Article

A powerful two-stage association test using case-control and case-parents genotype data.

Human heredity - 1 Jan 2009

Cheng K F, Lin W J, Chen J H, Horng J T

Abstract excerpt

OBJECTIVE: The performance of association tests based on case-control or case-parents substudy alone can be improved by jointly using genetic data from two substudies. However, genetic data from different sources may not be combinable due to population stratification. We propose a two-stage association test based on using combinability tests in stage 1 and association tests in stage 2. METHODS: The combinability...

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PMID: 19622894
DOI: 10.1159/000228925

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