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Article

Decreased behavioral impairments in an Alzheimer mice model by interfering with TNF-alpha metabolism.

Brain research bulletin - 28 Oct 2009

Giuliani Fabienne, Vernay André, Leuba Geneviève, Schenk Françoise

Abstract excerpt

The performance of mice expressing PDAPP (+/+ or +/-) was studied in the Morris place navigation task. Different lines of questions were investigated using PDAPP+/- mice in which the activity of the cytokine Tumor Necrosing Factor alpha (TNFalpha) was attenuated by chronic treatment with anti-TNF...

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Identifiers

PMID: 19622386
DOI: 10.1016/j.brainresbull.2009.07.009

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19622386-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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