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Article

A novel gene essential for the development of single positive thymocytes.

Molecular and cellular biology - 1 Sept 2009

Kakugawa Kiyokazu, Yasuda Takuwa, Miura Ikuo, Kobayashi Ayako, Fukiage Hitomi, Satoh Rumi, Matsuda Masashi, Koseki Haruhiko, Wakana Shigeharu, Kawamoto Hiroshi, Yoshida Hisahiro

Abstract excerpt

A critical step during intrathymic T-cell development is the transition of CD4(+) CD8(+) double-positive (DP) cells to the major histocompatibility complex class I (MHC-I)-restricted CD4(-) CD8(+) and MHC-II-restricted CD4(+) CD8(-) single-positive (SP) cell stage. Here, we identify a novel gene...

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Identifiers

PMID: 19620281
DOI: 10.1128/MCB.00793-09
PMCID: PMC2738282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19620281-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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