Article
The SNP ratio test: pathway analysis of genome-wide association datasets.
Bioinformatics (Oxford, England) - 15 Oct 2009
O'Dushlaine Colm, Kenny Elaine, Heron Elizabeth A, Segurado Ricardo, Gill Michael, Morris Derek W, Corvin Aiden
Abstract excerpt
UNLABELLED: We present a tool that assesses the enrichment of significant associations from genome-wide association studies (GWAS) in a pathway context. The SNP ratio test (SRT) compares the proportion of significant to all SNPs within genes that are part of a pathway and computes an empirical P-...
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