Article
Persistence of pandemic influenza H1N1 virus in young patients after oseltamivir therapy in the 2009-2010 season: a comparison with seasonal H1N1 with or without H275Y mutation.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Apr 2012
Kawai Naoki, Ikematsu Hideyuki, Iwaki Norio, Kondou Kunio, Hirotsu Nobuo, Kawashima Takashi, Maeda Tetsunari, Tanaka Osame, Doniwa Ken-ichi, Iwakuni Osamu, Egashira Keisuke, Yamaji Kouzaburo, Kashiwagi Seizaburo
Abstract excerpt
Comparison of the viral persistence of pandemic H1N1 (H1N1pdm) and seasonal H1N1 with or without H275Y mutation after oseltamivir therapy has not been adequately done. Virus was isolated before and on days 4-6 from the start of oseltamivir treatment for 158 cases of seasonal (2007-2008 and 2008-2009 seasons) or pandemic (2009-2010 season) H1N1 influenza. Sequence analysis was done for each season and NA...
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