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Host-derived glucose and its transporter in the obligate intracellular pathogen <i>Toxoplasma gondii</i> are dispensable by glutaminolysis

17 Jul 2009

Abstract excerpt

Toxoplasma gondii, as an obligate intracellular and promiscuous pathogen of mammalian cells, utilizes host sugars for energy and to generate glycoconjugates that are important to its survival and virulence. Here, we report that T. gondii glucose transporter (TgGT1) is proficient in transporting mannose, galactose, and fructose besides glucose, and serves as a major hexose transporter at its plasma membrane....

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PMID: 19617561
DOI: 10.1073/pnas.0903831106

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