Article
Identification and characterization of growth suppressors of Escherichia coli strains lacking phosphorolytic ribonucleases.
Journal of bacteriology - 1 Sept 2009
Jain Chaitanya
Abstract excerpt
RNases are involved in critical aspects of RNA metabolism in all organisms. Two classes of RNases that digest RNA from an end (exo-RNases) are known: RNases that use water as a nucleophile to catalyze RNA degradation (hydrolytic RNases) and RNases that use inorganic phosphate (phosphorolytic RNases). It has been shown previously that the absence of the two known Escherichia coli phosphorolytic RNases,...
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