Article
Bacillus subtilis mutants with knockouts of the genes encoding ribonucleases RNase Y and RNase J1 are viable, with major defects in cell morphology, sporulation, and competence.
Journal of bacteriology - 1 May 2013
Figaro Sabine, Durand Sylvain, Gilet Laetitia, Cayet Nadège, Sachse Martin, Condon Ciarán
Abstract excerpt
The genes encoding the ribonucleases RNase J1 and RNase Y have long been considered essential for Bacillus subtilis cell viability, even before there was concrete knowledge of their function as two of the most important enzymes for RNA turnover in this organism. Here we show that this characterization is incorrect and that ΔrnjA and Δrny mutants are both viable. As expected, both strains grow relatively slowly,...
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