Article
Neurofibroma development in NF1--insights into tumour initiation.
Trends in cell biology - 1 Aug 2009
Parrinello Simona, Lloyd Alison C
Abstract excerpt
Dissecting the early steps of tumourigenesis is key to our understanding of cancer biology. However, lack of knowledge of initiating mutations and the target 'cell of origin' has slowed progress towards this goal. Genetically engineered mouse models of the tumour-predisposition syndrome neurofibr...
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