Article
Integration of the plasmid encoding the synthesis of capsular antigen and murine toxin into Yersinia pestis chromosome.
Microbial pathogenesis - 1 Aug 1991
Protsenko O A, Filippov A A, Kutyrev V V
Abstract excerpt
Yersinia pestis, the causative agent of plague, usually carries three plasmids. The largest of them, a 60 megadalton (MDa) replicon designated pFra determines the synthesis of capsular antigen (fraction I) and murine toxin. Both products are involved in the expression of virulence. Previously, several cases of integration into the bacterial chromosome of the calcium dependence plasmid common to pathogenic...
Topics
- Antigens, Surface
- Bacterial Capsules
- Bacterial Toxins
- Blotting, Southern
- Mutation
- Plasmids
- Recombination, Genetic
- Yersinia pestis