Article
[The isolation and characteristics of variant plague microbes not producing the capsular antigen].
Mikrobiologicheskii zhurnal - 1 Jan 2000
Gvozdenko N A, Ryzhkov V Iu, Pavlovich N V
Abstract excerpt
Fifteen stable variants of Yersinia pestis strains exhibiting different degrees of virulence for white mice and guinea pigs were obtained. Multiple passages of the organisms at 37 degrees C in a fluid nutrient medium containing antiplague agglutinating serum were found to be the most efficient method for obtaining noncapsular forms of the plague agent. Acquisition of the Fra(-) phenotype both by wild and...
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