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Article

Effects of uridine on the growth and differentiation of HL-60 leukemia cells.

Leukemia research - 1 Jan 1991

Sokoloski J A, Lee C W, Handschumacher R E, Nigam A, Sartorelli A C

Abstract excerpt

HL-60 leukemia cells, induced to differentiate, activate a Na(+)-dependent nucleoside transport system, concomitant with a reduction in the nitrobenzylthioinosine (NBMPR)-sensitive facilitated transport of nucleosides. The consequence of these changes lead to the formation of intracellular pools of uridine. To examine the possible role of accumulated uridine in the commitment of HL-60 leukemia cells to undergo...

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Identifiers

PMID: 1961008
DOI: 10.1016/0145-2126(91)90111-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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