Article
Effect of mammalian cell differentiation on response to exogenous 5-aminolevulinic acid.
Photochemistry and photobiology - 1 Feb 1999
Li G, Szewczuk M R, Pottier R H, Kennedy J C
Abstract excerpt
Many different types of mammalian cells accumulate fluorescing and photosensitizing concentrations of protoporphyrin IX (PpIX) when exposed to exogenous 5-aminolevulinic acid (ALA) in vivo or in vitro. Most types of malignant cells accumulate substantially more ALA-induced PpIX than do the normal cells from which they arose. Most types of malignant cells also are less differentiated than their normal...
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