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Article

Envelope Recombination: A Major Driver in Shaping Retroviral Diversification and Evolution within the Host Genome.

Viruses - 31 Aug 2023

Chabukswar Saili, Grandi Nicole, Lin Liang-Tzung, Tramontano Enzo

Abstract excerpt

Endogenous retroviruses (ERVs) are integrated into host DNA as the result of ancient germ line infections, primarily by extinct exogenous retroviruses. Thus, vertebrates' genomes contain thousands of ERV copies, providing a "fossil" record for ancestral retroviral diversity and its evolution within the host genome. Like other retroviruses, the ERV proviral sequence consists of gag, pro, pol, and env genes flanked...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37766262
DOI: 10.3390/v15091856
PMCID: PMC10536682

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