Article
Association between total immunoglobulin E and antibody responses to naturally acquired Ascaris lumbricoides infection and polymorphisms of immune system-related LIG4, TNFSF13B and IRS2 genes.
Clinical and experimental immunology - 1 Aug 2009
Acevedo N, Mercado D, Vergara C, Sánchez J, Kennedy M W, Jiménez S, Fernández A M, Gutiérrez M, Puerta L, Caraballo L
Abstract excerpt
The 13q33-34 region harbours a susceptibility locus to Ascaris lumbricoides, although the underlying genes are unknown. Immunoglobulin (Ig)E and IgG confer protective immunity and here we sought to investigate in an endemic population whether LIG4, TNFSF13B and IRS2 genes influence IgE and IgG le...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.