Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STAT3 as a Central Regulator of Tumor Metastases

1 Jun 2009

Abstract excerpt

Metastasis is a major cause of morbidity and mortality in patients with cancer. The molecular mechanisms that control metastasis are related to alterations in various oncogenes, tumor suppressor genes, metastasis suppressor genes, and growth factors and their receptors. These abnormalities affect the downstream signal transduction pathways involved in the control of cell growth and other malignant properties. One...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cancer-related gene regulation
Share to Cytokine Signaling Pathways and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19601811
DOI: 10.2174/156652409788488720

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STAT3 as a Central Regulator of Tumor MetastasesPMID 19601811Read ↗

Regulation of Metastases by Signal Transducer and Activator of Transcription 3 Signaling Pathway: Clinical ImplicationsSemantic proximity Read ↗

Targeting the Cytoplasmic and Nuclear Functions of Signal Transducers and Activators of Transcription 3 for Cancer TherapySemantic proximity Read ↗

STAT3 Signaling in CancerSemantic proximity Read ↗

The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.Semantic proximity Read ↗

STAT3 SIGNALING: Anticancer Strategies and ChallengesSemantic proximity Read ↗

Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discoverySemantic proximity Read ↗

Critical analysis of the potential for targeting STAT3 in human malignancySemantic proximity Read ↗

STAT3 Target Genes Relevant to Human CancersSemantic proximity Read ↗

The Multifaced Role of STAT3 in Cancer and Its Implication for Anticancer TherapySemantic proximity Read ↗

Role of STAT3 in cancer cell epithelial‑mesenchymal transition (Review)Semantic proximity Read ↗

Overview of the STAT‑3 signaling pathway in cancer and the development of specific inhibitors (Review)Semantic proximity Read ↗

Role of STAT3 in lung cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.