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Role of STAT3 in cancer cell epithelial‑mesenchymal transition (Review)

13 Mar 2024

Abstract excerpt

Since its discovery, the role of the transcription factor, signal transducer and activator of transcription 3 (STAT3), in both normal physiology and the pathology of numerous diseases, including cancer, has been extensively studied. STAT3 is aberrantly activated in different types of cancer, fulfilling a critical role in cancer progression. The biological process, epithelial‑mesenchymal transition (EMT), is...

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PMID: 38488027
DOI: 10.3892/ijo.2024.5636

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