Article
Effect of mutator P. aeruginosa on antibiotic resistance acquisition and respiratory function in cystic fibrosis.
Pediatric pulmonology - 1 Aug 2009
Ferroni Agnes, Guillemot Didier, Moumile Kaoutar, Bernede Claire, Le Bourgeois Muriel, Waernessyckle Serge, Descamps Philippe, Sermet-Gaudelus Isabelle, Lenoir Gérard, Berche Patrick, Taddei François
Abstract excerpt
BACKGROUND: Cystic fibrosis patients suffer from recurrent bacterial infections that result in progressive deterioration of their respiratory function. Despite intensive antibiotic treatment, Pseudomonas aeruginosa is the main cause of such infections, with clones progressively developing multiple antibiotic resistance. We determined the relationship between the presence of P. aeruginosa mutator strains and...
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