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Article

Hypermutability in environmental Pseudomonas aeruginosa and in populations causing pulmonary infection in individuals with cystic fibrosis.

Microbiology (Reading, England) - 1 Jun 2007

Kenna Dervla T, Doherty Catherine J, Foweraker Juliet, Macaskill Lisa, Barcus Victoria A, Govan John R W

Abstract excerpt

Pseudomonas aeruginosa is the pathogen most commonly associated with morbidity and mortality in cystic fibrosis (CF) patients. The host-pathogen interactions responsible for progressive CF lung diseases are complex. However, there is growing interest in the role of hypermutable P. aeruginosa (that is, those strains with an increased mutation frequency due to mutations in mismatch repair and error prevention...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17526842
DOI: 10.1099/mic.0.2006/005082-0

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