Article
On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network.
The International journal of developmental biology - 1 Jan 2009
García-Ceca Javier, Jiménez Eva, Alfaro David, Cejalvo Teresa, Chumley Michael J, Henkemeyer Mark, Muñoz Juan-José, Zapata Agustín G
Abstract excerpt
In the current study, we extend our own previous results on the thymocyte phenotype of EphB2 and/or EphB3 deficient mice by analyzing the phenotype and the histological organization of their thymic epithelial stroma. All studied adult EphB-deficient thymi showed profound alterations with respect to the wild-type (WT) ones. Each mutant exhibited a specific phenotype, but also showed common features including...
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