Article
EphB receptors, mainly EphB3, contribute to the proper development of cortical thymic epithelial cells.
Organogenesis - 2 Oct 2017
Montero-Herradón Sara, García-Ceca Javier, Zapata Agustín G
Abstract excerpt
EphB and their ligands ephrin-B are an important family of protein tyrosine kinase receptors involved in thymocyte-thymic epithelial cell interactions known to be key for the maturation of both thymic cell components. In the present study, we have analyzed the maturation of cortical thymic epithelium in EphB-deficient thymuses evaluating the relative relevance of EphB2 and EphB3 in the process. Results support a...
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