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Article

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

13 Jul 2009

Abstract excerpt

BCL2 and MYC are oncogenes commonly deregulated in lymphomas. Concurrent BCL2 and MYC translocations (BCL2(+)/MYC(+)) were identified in 54 samples by karyotype and/or fluorescence in situ hybridization with the aim of correlating clinical and cytogenetic characteristics to overall survival. BCL2(+)/MYC(+) lymphomas were diagnosed as B-cell lymphoma unclassifiable (BCLU; n = 36) with features intermediate between...

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PMID: 19597184
DOI: 10.1182/blood-2009-03-212191

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