Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two novel NPM1 mutations in a therapy-responder AML patient.

Hematological oncology - 1 Sept 2010

Pianta Annalisa, Fabbro Dora, Damiani Daniela, Tiribelli Mario, Fanin Renato, Franzoni Alessandra, Romanello Milena, Tell Gianluca, Di Loreto Carla, Damante Giuseppe

Abstract excerpt

Nucleophosmin 1 (NPM1) is an abundant phosphoprotein mainly located in the nucleolus but also shuttling between the nucleus and cytoplasm. NPM1 has been proposed to be involved in synthesis and processing of ribosomal RNA, regulation of chromatin structure and transport of rRNA and ribosomal prot...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleolus
Share to Exons
Share to NPM1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Transfection

Source

Identifiers

PMID: 19593743
DOI: 10.1002/hon.906

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19593743-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two novel NPM1 mutations in a therapy-responder AML patient.PMID 19593743Read ↗

Current status and future perspectives in targeted therapy of NPM1-mutated AML.Semantic proximity Read ↗

When the good go bad: Mutant NPM1 in acute myeloid leukemia.Semantic proximity Read ↗

Functions of the native NPM1 protein and its leukemic mutant.Semantic proximity Read ↗

Nucleophosmin: A versatile molecule associated with hematological malignanciesSemantic proximity Read ↗

Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy?Semantic proximity Read ↗

Role of nucleophosmin in acute myeloid leukemia.Semantic proximity Read ↗

Nucleophosmin mutations in acute myeloid leukemia: a tale of protein unfolding and mislocalization.Semantic proximity Read ↗

[Nucleophosmin mutations in hematological malignancies - review].Semantic proximity Read ↗

A Curious Novel Combination of Nucleophosmin (NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML).Semantic proximity Read ↗

A novel type of NPM1 mutation characterized by multiple internal tandem repeats in a case of cytogenetically normal acute myeloid leukemia.Semantic proximity Read ↗

Detection of exon 12 type A mutation of NPM1 gene in IMS-M2 cell line.Semantic proximity Read ↗

Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.