Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pilin antigenic variation occurs independently of the RecBCD pathway in Neisseria gonorrhoeae.

Journal of bacteriology - 1 Sept 2009

Helm R Allen, Seifert H Steven

Abstract excerpt

Type IV pilus expression has been strongly implicated in the virulence of Neisseria gonorrhoeae, the causative agent of gonorrhea. In Neisseria, these pili undergo frequent antigenic variation (Av), which is presumed to allow reinfection of high-risk groups. Pilin Av is the result of RecA-mediated recombination events between the gene encoding the major pilin subunit (pilE) and multiple silent pilin locus (pilS)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigenic Variation
Share to DNA Damage
Share to DNA Repair

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Exodeoxyribonuclease V

Share to Fimbriae, Bacterial

Share to Fimbriae Proteins

Share to Gene Expression Regulation, Bacterial

Share to Neisseria gonorrhoeae

Source

Open in PubMed Open full text

Identifiers

PMID: 19592592
DOI: 10.1128/JB.00535-09
PMCID: PMC2737965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pilin antigenic variation occurs independently of the RecBCD pathway in Neisseria gonorrhoeae.PMID 19592592Read ↗

Role for the RecBCD recombination pathway for pilE gene variation in repair-proficient Neisseria gonorrhoeae.Semantic proximity Read ↗

Characterization of the recD gene of Neisseria gonorrhoeae MS11 and the effect of recD inactivation on pilin variation and DNA transformation.Semantic proximity Read ↗

Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation.Semantic proximity Read ↗

Loss of both Holliday junction processing pathways is synthetically lethal in the presence of gonococcal pilin antigenic variationSemantic proximity Read ↗

Analysis of Pilin Antigenic Variation in Neisseria meningitidis by Next-Generation Sequencing.Semantic proximity Read ↗

The frequency and rate of pilin antigenic variation in <i>Neisseria gonorrhoeae</i>Semantic proximity Read ↗

Roles of therecJandrecNGenes in Homologous Recombination and DNA Repair Pathways ofNeisseria gonorrhoeaeSemantic proximity Read ↗

CRISPRi targeting to the Neisseria gonorrhoeae R-loop or G4 mutant region restores pilin antigenic variation.Semantic proximity Read ↗

Analyzing Neisseria gonorrhoeae Pilin Antigenic Variation Using 454 Sequencing Technology.Semantic proximity Read ↗

An Alternative DNA Structure Is Necessary for Pilin Antigenic Variation in <i>Neisseria gonorrhoeae</i>Semantic proximity Read ↗

Pilin gene variation inNeisseria gonorrhoeae: reassessing the old paradigmsSemantic proximity Read ↗

Neisseria gonorrhoeae recJ mutants show defects in recombinational repair of alkylated bases and UV-induced pyrimidine dimers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.