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Article

A brain-derived neurotrophic factor haplotype is associated with therapeutic response in obsessive-compulsive disorder.

Biological psychiatry - 1 Oct 2009

Real Eva, Gratacòs Mònica, Soria Virginia, Escaramís Geòrgia, Alonso Pino, Segalàs Cinto, Bayés Mònica, de Cid Rafael, Menchón José M, Estivill Xavier

Abstract excerpt

BACKGROUND: Several clinical and genetic studies have focused on the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of various mental disorders. Recent lines of evidence regarding the network hypothesis of treatment outcome point towards the involvement of BDNF variants i...

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Source

Identifiers

PMID: 19589503
DOI: 10.1016/j.biopsych.2009.05.017

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19589503-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A brain-derived neurotrophic factor haplotype is associated with therapeutic response in obsessive-compulsive disorder.PMID 19589503Read ↗

Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorder.Semantic proximity Read ↗

Association study between BDNF gene variants and Mexican patients with obsessive-compulsive disorder.Semantic proximity Read ↗

A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders.Semantic proximity Read ↗

Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder.Semantic proximity Read ↗

The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD).Semantic proximity Read ↗

Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response.Semantic proximity Read ↗

Association of serum BDNF level and Val66Met polymorphism with response to treatment in patients of major depressive disease: A step towards personalized therapy.Semantic proximity Read ↗

The role of the brain-derived neurotrophic factor SNP rs2883187 in the phenotypic expression of obsessive-compulsive disorder.Semantic proximity Read ↗

Brain-derived neurotrophic factor (BDNF) plasma levels in drug-naïve OCD patients are lower than those in healthy people, but are not lower than those in drug-treated OCD patients.Semantic proximity Read ↗

Serum brain-derived neurotrophic factor, Val66Met polymorphism and open-label SSRI treatment response in Major Depressive Disorder.Semantic proximity Read ↗

Meta-analysis and association of brain-derived neurotrophic factor (BDNF) gene with obsessive-compulsive disorder.Semantic proximity Read ↗

Variation in the BDNF Val66Met polymorphism and response to cognitive-behavior therapy in obsessive-compulsive disorder.Semantic proximity Read ↗

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