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Article

Variation in the BDNF Val66Met polymorphism and response to cognitive-behavior therapy in obsessive-compulsive disorder.

European psychiatry : the journal of the Association of European Psychiatrists - 1 Jul 2012

Fullana M A, Alonso P, Gratacòs M, Jaurrieta N, Jiménez-Murcia S, Segalàs C, Real E, Estivill X, Menchón J M

Abstract excerpt

BACKGROUND: Recent research suggests that the brain-derived neurotrophic factor (BDNF) may play a role in extinction learning. The goal of this study was to test whether variation in the BDNF Val66Met polymorphism is related to treatment response to exposure-based cognitive-behavior therapy (CBT), a form of extinction learning, in obsessive-compulsive disorder (OCD). METHODS: One hundred and six OCD patients from...

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Source

Identifiers

PMID: 22153732
DOI: 10.1016/j.eurpsy.2011.09.005

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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