Article
Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins.
PloS one - 9 Jul 2009
Schaaf Cheri A, Misulovin Ziva, Sahota Gurmukh, Siddiqui Akbar M, Schwartz Yuri B, Kahn Tatyana G, Pirrotta Vincenzo, Gause Maria, Dorsett Dale
Abstract excerpt
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active genes, and is generally absent from regions in...
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