Article
Rings and Bricks: Expression of Cohesin Components is Dynamic during Development and Adult Life.
International journal of molecular sciences - 1 Feb 2018
Bettini Laura Rachele, Graziola Federica, Fazio Grazia, Grazioli Paolo, Scagliotti Valeria, Pasquini Mariavittoria, Cazzaniga Giovanni, Biondi Andrea, Larizza Lidia, Selicorni Angelo, Gaston-Massuet Carles, Massa Valentina
Abstract excerpt
Cohesin complex components exert fundamental roles in animal cells, both canonical in cell cycle and non-canonical in gene expression regulation. Germline mutations in genes coding for cohesins result in developmental disorders named cohesinopaties, of which Cornelia de Lange syndrome (CdLS) is the best-known entity. However, a basic description of mammalian expression pattern of cohesins in a physiologic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
