Article
The novel tumor-suppressor Mel-18 in prostate cancer: its functional polymorphism, expression and clinical significance.
International journal of cancer - 15 Dec 2009
Wang Wei, Yuasa Takeshi, Tsuchiya Norihiko, Ma Zhiyong, Maita Shinya, Narita Shintaro, Kumazawa Teruaki, Inoue Takamitsu, Tsuruta Hiroshi, Horikawa Yohei, Saito Mitsuru, Hu Weilie, Ogawa Osamu, Habuchi Tomonori
Abstract excerpt
Mel-18 is a member of the polycomb group (PcG) proteins, which are chromatin regulatory factors and play important roles in development and oncogenesis. This study was designed to investigate the clinical and prognostic significance of Mel-18 in patients with prostate cancer. A total of 539 native Japanese subjects consisting of 393 prostate cancer patients and 146 controls were enrolled in this study. Mel-18...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
