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Article

miR-490-3p modulates the progression of prostate cancer through regulating histone deacetylase 2.

1 Jan 2019

Abstract excerpt

OBJECTIVE: microRNAs (miRNAs) were regarded as critical participators for human cancers progression including prostate cancer (PCa) and have the potential to be used as treatment targets for cancers. Herein, we validated a tumor-suppressive miRNA, miR-490-3p, which may suppress PCa progression. Histone deacetylase 2 (HDAC2) is a protein that aberrantly expressed in several cancers. However, the role of HDAC2 in...

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PMID: 30720161
DOI: 10.26355/eurrev_201901_16866

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