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Article

BAP18 coactivates androgen receptor action and promotes prostate cancer progression

25 May 2016

Abstract excerpt

BPTF associated protein of 18 kDa (BAP18) has been reported as a component of MLL1-WDR5 complex. However, BAP18 is an uncharacterized protein. The detailed biological functions of BAP18 and underlying mechanisms have not been defined. Androgen receptor (AR), a member of transcription factor, plays an essential role in prostate cancer (PCa) and castration-resistant prostate cancer (CRPC) progression. Here, we...

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PMID: 27226492
DOI: 10.1093/nar/gkw472

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