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Article

B-cell based gene therapy for autoimmune diseases.

Infectious disorders drug targets - 1 Jun 2012

Scott David W, Zhang Ai-Hong, Su Yan

Abstract excerpt

The essence of the adaptive immune system is self tolerance, which is maintained by various central and peripheral check points. However, the tolerance mechanisms can be broken in autoimmune disease conditions due to genetic predisposition and environmental triggers. As a consequence, a patient's tissue is attacked by his/her own adaptive immune system. An ideal therapy for autoimmune diseases should include...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22394178
DOI: 10.2174/187152612800564383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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