Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice

10 Sept 2014

Abstract excerpt

Olfactomedin 2 (Olfm2) is a secretory glycoprotein belonging to the family of olfactomedin domain-containing proteins. A previous study has shown that a mutation in OLFM2 is associated with primary open angle glaucoma in Japanese patients. In the present study, we generated Olfm2 deficient mice by replacing the Olfm2 gene with the LacZ gene. The loss of Olfm2 resulted in no gross abnormalities. However, Olfm2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma and retinal disorders
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25218043
DOI: 10.1016/j.expneurol.2014.09.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in micePMID 25218043Read ↗

Mutated olfactomedin 1 in the interphotoreceptor matrix of the mouse retina causes functional deficits and vulnerability to light damage.Semantic proximity Read ↗

Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon.Semantic proximity Read ↗

Identification and functional characterisation of genetic variants in OLFM2 in children with developmental eye disorders.Semantic proximity Read ↗

Anxiety- and depressive-like behaviors in olfactory deficient Cnga2 knockout mice.Semantic proximity Read ↗

The genetics of olfaction.Semantic proximity Read ↗

Mice deficient in G(olf) are anosmic.Semantic proximity Read ↗

Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice.Semantic proximity Read ↗

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulbSemantic proximity Read ↗

Spatiotemporal regulation by downstream genes of <i>Prok2</i> in olfactory system: from development to functionSemantic proximity Read ↗

Impact of the Usher syndrome on olfaction.Semantic proximity Read ↗

GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation.Semantic proximity Read ↗

Characterization and differential expression of a human gene family of olfactomedin-related proteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.