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Article

Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Feb 2009

Santos-López Gerardo, Scior Thomas, Borraz-Argüello María del Tránsito, Vallejo-Ruiz Verónica, Herrera-Camacho Irma, Tapia-Ramírez José, Reyes-Leyva Julio

Abstract excerpt

A point mutation from guanine (G) to adenine (A) at nucleotide position 1081 in the hemagglutinin-neuraminidase (HN) gene has been associated with neurovirulence of Urabe AM9 mumps virus vaccine. This mutation corresponds to a glutamic acid (E) to lysine (K) change at position 335 in the HN glycoprotein. We have experimentally demonstrated that two variants of Urabe AM9 strain (HN-A1081 and HN-G1081) differ in...

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PMID: 19578626
DOI: 10.1590/s1413-86702009000100007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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