Article
Hemagglutinin-neuraminidase (HN) amino acid alterations in neutralization escape mutants of Kilham mumps virus.
Virus research - 1 Oct 1990
Kövamees J, Rydbeck R, Orvell C, Norrby E
Abstract excerpt
The hemagglutinin-neuraminidase genes of the Kilham strain of mumps virus and three neutralization escape mutants (M11, M12 and M13) of this strain (Löve et al., 1985a) were sequenced using their genomes as template. The predicted amino acid sequences were compared. While one mutant had only one amino acid substitution the other two mutants had four and five respectively. A putative region for the epitope of the...
Topics
- Amino Acid Sequence
- Enzyme-Linked Immunosorbent Assay
- Hemagglutinins, Viral
- Molecular Sequence Data
- Mumps virus
- Mutation
- Neuraminidase
- RNA
