Article
Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.
Scientific reports - 6 Sept 2018
Gouma Sigrid, Vermeire Tessa, Van Gucht Steven, Martens Lennart, Hutse Veronik, Cremer Jeroen, Rota Paul A, Leroux-Roels Geert, Koopmans Marion, van Binnendijk Rob, Vandermarliere Elien
Abstract excerpt
The surface proteins of the mumps virus, the fusion protein (F) and haemagglutinin-neuraminidase (HN), are key factors in mumps pathogenesis and are important targets for the immune response during mumps virus infection. We compared the predicted amino acid sequences of the F and HN genes from Dutch mumps virus samples from the pre-vaccine era (1957-1982) with mumps virus genotype G strains (from 2004 onwards)....
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