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Article

Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.

Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2009

Coon Charles I, Fiering Steven, Gaudet Justin, Wyatt Colby A, Brinckerhoff Constance E

Abstract excerpt

Matrix metalloproteinases (MMPs) comprise a family of more than 20 members, each with the ability to degrade components of the extracellular matrix. The interstitial collagenases have the unique capacity to degrade the stromal collagens, types I, II and III, the body's most abundant proteins. These collagenases include MMP-1, MMP-8, MMP-13 and MMP-14. MMP-1, with a very broad expression pattern, has major roles...

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Identifiers

PMID: 19577645
DOI: 10.1016/j.matbio.2009.06.003
PMCID: PMC2783711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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