Article
[Abnormal expression of c-myc, p53, p16 protein and GNAS1 gene mutation in fibrous dysplasia].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 May 2009
Tang Juan, Zhao Hong-ye, Zheng Li, Zhang Hui-zhen, Jiang Zhi-ming
Abstract excerpt
OBJECTIVE: To study the significance of c-myc, p53 and p16 protein expression in fibrous dysplasia, to detect the GNAS1 gene mutation in fibrous dysplasia, and to explore the property of fibrous dysplasia. METHODS: The expression of c-myc, p53 and p16 protein was evaluated by immunohistochemistry SP method in 35 cases of fibrous dysplasia including 1 FD with malignancy, 1 Mazabraud syndrome and 20 control cases...
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