Article
Rare genotypes of protein Z gene are a risk factor for premature myocardial infarction but not protein Z plasma level.
Thrombosis and haemostasis - 1 Jul 2009
Le Cam-Duchez Véronique, Soria Claudine, Dit Sollier Claire Bal, Borg Jeanne-Yvonne, Coudert Mathieu, Montalescot Gilles, Esposito Gaétan, Drouet Ludovic, Collet Jean-Philippe
Abstract excerpt
Protein Z (PZ) is the cofactor of PZ dependent inhibitor (ZPI) that inhibits activated coagulation factor X. PZ was expected to play a role in coronary artery disease (CAD) but with inconsistent clinical findings. We therefore evaluated whether PZ plasma level and/or three genetic variants encoding for low PZ plasma level were associated with premature CAD in stable young post-myocardial infarction (MI) patients....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
