Article
Low protein Z levels but not the protein Z gene G79A polymorphism are a risk factor for ischemic stroke.
Thrombosis research - 1 Jan 2008
van Goor M P J, Dippel D W J, Jie K S-G, de Maat M P M, Koudstaal P J, Leebeek F W G
Abstract excerpt
BACKGROUND: Protein Z (PZ) is a vitamin K-dependent plasma protein that plays a role in both pro-and anticoagulant pathways, but its exact physiological function remains unclear. The aim of this study was to determine the association between the G79A PZ gene polymorphism in intron F, PZ levels and the occurrence of ischemic stroke. METHODS: We performed a case-control study in 118 Caucasian patients with first...
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