Article
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
Human molecular genetics - 15 Sept 2009
Estrada Karol, Krawczak Michael, Schreiber Stefan, van Duijn Kate, Stolk Lisette, van Meurs Joyce B J, Liu Fan, Penninx Brenda W J H, Smit Jan H, Vogelzangs Nicole, Hottenga Jouke Jan, Willemsen Gonneke, de Geus Eco J C, Lorentzon Mattias, von Eller-Eberstein Huberta, Lips Paul, Schoor Natascha, Pop Victor, de Keijzer Jules, Hofman Albert, Aulchenko Yurii S, Oostra Ben A, Ohlsson Claes, Boomsma Dorret I, Uitterlinden Andre G, van Duijn Cornelia M, Rivadeneira Fernando, Kayser Manfred
Abstract excerpt
Northwestern Europeans are among the tallest of human populations. The increase in body height in these people appears to have reached a plateau, suggesting the ubiquitous presence of an optimal environment in which genetic factors may have exerted a particularly strong influence on human growth. Therefore, we performed a genome-wide association study (GWAS) of body height using 2.2 million markers in 10 074...
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