Article
Results from a prostate cancer admixture mapping study in African-American men.
Human genetics - 1 Nov 2009
Bock Cathryn Hufford, Schwartz Ann G, Ruterbusch Julie J, Levin Albert M, Neslund-Dudas Christine, Land Susan J, Wenzlaff Angela S, Reich David, McKeigue Paul, Chen Wei, Heath Elisabeth I, Powell Isaac J, Kittles Rick A, Rybicki Benjamin A
Abstract excerpt
There are considerable racial disparities in prostate cancer risk, with a 60% higher incidence rate among African-American (AA) men compared with European-American (EA) men, and a 2.4-fold higher mortality rate in AA men than in EA men. Recently, studies have implicated several African-ancestry associated prostate cancer susceptibility loci on chromosome 8q24. In the current study, we performed admixture mapping...
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