Article
Pharmacogenetic impact of VKORC1 and CYP2C9 allelic variants on warfarin dose requirements in a hispanic population isolate.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Feb 2010
Palacio Lina, Falla Diana, Tobon Ignacio, Mejia Fernando, Lewis John E, Martinez Ariel F, Arcos-Burgos Mauricio, Camargo Mauricio
Abstract excerpt
Warfarin is the most prescribed oral anticoagulant worldwide. Because of the complexity of warfarin therapy, we attempted to dissect genetic from bioenvironmental factors influencing warfarin dose responses in individuals of a genetic isolate of Hispanic ancestry. A total of 191 patients with sta...
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