Article
Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.
Journal of experimental & clinical cancer research : CR - 30 Jun 2009
Guan Xiaoxiang, Zhao Hui, Niu Jiangong, Tan Dongfeng, Ajani Jaffer A, Wei Qingyi
Abstract excerpt
BACKGROUND: Some TGFB1 and VEGF polymorphisms are believed to be functional. Given that these genes are involved in tumor growth and progression including angiogenesis, dissemination, and invasiveness, we hypothesized that these polymorphisms would be associated with survival in patients with gastric cancer. METHODS: We genotyped TGFB1 -509 C>T, +1869 T>C, and +915 G>C and VEGF -1498T>C, -634G>C, and +936C>T in...
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