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Article

Association of the TGFβ gene family with microenvironmental features of gastric cancer and prediction of response to immunotherapy

2 Sept 2022

Abstract excerpt

In the complex tumor microenvironment, TGFβ is a pleiotropic cytokine involved in regulating cellular processes such as cancer cell proliferation, apoptosis and metastasis. TGFβ defines three subtypes (TGFβ1, TGFβ2, and TGFβ3), of which TGFβ is highly expressed in many cancers, especially those showing high dissemination potential. In addition, increased expression of TGFβ in multiple cancers is usually...

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PMID: 36119489
DOI: 10.3389/fonc.2022.920599

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