Article
The functional significance behind expressing two IL-8 receptor types on PMN.
Journal of leukocyte biology - 1 Sept 2009
Stillie RoseMarie, Farooq Shukkur Muhammed, Gordon John R, Stadnyk Andrew W
Abstract excerpt
PMN are critical to innate immunity and are fundamental to antibacterial defense. To localize to sites of infection, PMN possess receptors that detect chemoattractant stimuli elicited at the site, such as chemokines, complement split products, or bioactive lipids. Signaling through these receptors stimulates chemotaxis toward the site of infection but also activates a number of biochemical processes, with the...
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