Article
Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration.
Journal of leukocyte biology - 1 Feb 2006
Buckley Christopher D, Ross Ewan A, McGettrick Helen M, Osborne Chloe E, Haworth Oliver, Schmutz Caroline, Stone Philip C W, Salmon Mike, Matharu Nick M, Vohra Rajiv K, Nash Gerard B, Rainger G Ed
Abstract excerpt
Recent studies have demonstrated that neutrophils are not a homogenous population of cells. Here, we have identified a subset of human neutrophils with a distinct profile of cell-surface receptors [CD54(high), CXC chemokine receptor 1(low) (CXCR1(low))], which represent cells that have migrated through an endothelial monolayer and then re-emerged by reverse transmigration (RT). RT neutrophils, when in contact...
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