Article
Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit.
Scientific reports - 15 Feb 2016
Laricchiuta Daniela, Saba Luana, De Bartolo Paola, Caioli Silvia, Zona Cristina, Petrosini Laura
Abstract excerpt
Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction. We recently developed an innovative experimental model of individual differences in approach and avoidance behaviors, classifying the mice as Approaching,...
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