Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells.

Proteomics - 1 Jun 2009

Trott Deborah, McManus Ciara A, Martin Jody L, Brennan Bryony, Dunn Michael J, Rose Marlene L

Abstract excerpt

Recent studies have suggested a protective role of hsp27 against atherosclerosis and transplant graft vasculopathy. Here we have investigated the effects of over-expression of wild-type hsp27 and its phosphorylation mimics on proliferation of human endothelial cells (ECs) and smooth muscle cells (SMCs). ECs and SMCs cultured from human blood vessels or cells lines (human microvascular endothelial cell line and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to Cell Growth Processes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Gel, Two-Dimensional

Share to Endothelial Cells

Share to Extracellular Signal-Regulated MAP Kinases

Share to HSP27 Heat-Shock Proteins

Share to Muscle, Smooth

Share to Proteome

Source

Identifiers

PMID: 19562804
DOI: 10.1002/pmic.200800961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of phosphorylated hsp27 on proliferation of human endothelial and smooth muscle cells.PMID 19562804Read ↗

Overexpression of human Hsp27 inhibits serum-induced proliferation in airway smooth muscle myocytes and confers resistance to hydrogen peroxide cytotoxicity.Semantic proximity Read ↗

Inhibition of Daxx-mediated apoptosis by heat shock protein 27.Semantic proximity Read ↗

Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism.Semantic proximity Read ↗

Heat shock protein 27 (HSP27): biomarker of disease and therapeutic targetSemantic proximity Read ↗

A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.Semantic proximity Read ↗

Functional relevance of tetraspanin CD9 in vascular smooth muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia.Semantic proximity Read ↗

Modification and Reorganization of the Cytoprotective Cellular Chaperone Hsp27 during Herpes Simplex Virus Type 1 InfectionSemantic proximity Read ↗

Chaperone-like activity of monomeric human 14-3-3ζ on different protein substrates.Semantic proximity Read ↗

MARCKS silencing differentially affects human vascular smooth muscle and endothelial cell phenotypes to inhibit neointimal hyperplasia in saphenous vein.Semantic proximity Read ↗

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNASemantic proximity Read ↗

Overexpression of wild-type heat shock protein 27 and a nonphosphorylatable heat shock protein 27 mutant protects against ischemia/reperfusion injury in a transgenic mouse model.Semantic proximity Read ↗

Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.