Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array.

doi:10.1371/journal.pone.0006034

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array.

PloS one - 29 Jun 2009

Sõber Siim, Org Elin, Kepp Katrin, Juhanson Peeter, Eyheramendy Susana, Gieger Christian, Lichtner Peter, Klopp Norman, Veldre Gudrun, Viigimaa Margus, Döring Angela, Putku Margus, Kelgo Piret, Shaw-Hawkins Sue, Howard Philip, Onipinla Abiodun, Dobson Richard J, Newhouse Stephen J, Brown Morris, Dominiczak Anna, Connell John, Samani Nilesh, Farrall Martin, Caulfield Mark J, Munroe Patricia B, Illig Thomas, Wichmann H-Erich, Meitinger Thomas, Laan Maris

Abstract excerpt

The outcome of Genome-Wide Association Studies (GWAS) has challenged the field of blood pressure (BP) genetics as previous candidate genes have not been among the top loci in these scans. We used Affymetrix 500K genotyping data of KORA S3 cohort (n = 1,644; Southern-Germany) to address (i) SNP coverage in 160 BP candidate genes; (ii) the evidence for associations with BP traits in genome-wide and replication...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Genetic Markers

Share to Genome, Human

Share to Genome-Wide Association Study

Share to Models, Genetic

Share to Oligonucleotide Array Sequence Analysis

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19562039
DOI: 10.1371/journal.pone.0006034
PMCID: PMC2699027

Genes

LEPR
DBP
LEP
PTGER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array.PMID 19562039Read ↗

Loci influencing blood pressure identified using a cardiovascular gene-centric array.Semantic proximity Read ↗

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Semantic proximity Read ↗

Genome-wide analysis in over 1 million individuals reveals over 2,000 independent genetic signals for blood pressureSemantic proximity Read ↗

Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicatedSemantic proximity Read ↗

Genome-wide association study identifies eight loci associated with blood pressure.Semantic proximity Read ↗

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Semantic proximity Read ↗

Recent Findings in the Genetics of Blood Pressure and Hypertension TraitsSemantic proximity Read ↗

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.Semantic proximity Read ↗

Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.Semantic proximity Read ↗

Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.Semantic proximity Read ↗

Blood pressure loci identified with a gene-centric array.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.